Gene: leucine-3 IL
leucine-3
locus: leu-3
locus_name: leucine-3
organism_type: B
chromosome_number: I
chromosome_side: L
link_group: IL
cultural_requirements: IL. Right of the In(OY323) left breakpoint and nit-2 (12 to 18%). Left of cyt-1 (5 to 8%) and T(OY321) (57, 816, PB; D.D. Perkins, N.B. Raju, and E.G. Barry, in preparation). (868)Requires leucine (867, 868). Regulatory mutation; prevents synthesis of alpha-isopropylmalate isomerase and beta-isopropylmalate dehydrogenase and prevents full derepression of alpha-isopropylmalate synthetase; also involved in regulation of isoleucine and valine synthesis, q.v. (427, 771, 833) (Fig. 15). The original allele, 47313, is leaky, but some other alleles, e.g., R156, are not.
enzyme_id: 1
Enzyme: (a)-isopropylmalateisomerase, (B)-isopropylmalatedehydrogenase
anid_name:
near_l: In(OY323) left breakpoint and nit-2 (12 to 18%)
near_r: cyt-1 (5 to 8%) and T(OY321)
neu_name:
supplement: leucine
image_url:
Strains
References
