FGSC #39

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Reporting Genes: su(met-7) al-2

Species: crassa

Allele: S1 15300

Alternate Strain Number: 9046

Depositor: DDP

Linkage Group: IR IR

Mating Type: a

Species Number: 10

Genetic Background: M

Deposit Sheet ↗

Genes

Locus	Cultural Requirements	Link Group	Type
al-2	IR. Right of os-5 (<1%) and T(STL76). Left of arg-6(1%) and al-1 (797, 802, 808, 816, 818). Included in duplications from Tp(T54M94), confirming location left of arg-6(808). (482) Carotenoids absent or abnormal, but steroids produced (398). Blocked in microsomal fraction and defective in phytoene synthetase (445), a particulate enzyme (445 and references cited therein) (Fig. 9). Tracer experiments indicate a lesion between prephytoene pyrophosphate and phytoene (572). Alleles include those resulting in white and pale rose-white, e.g., 15300 and Y254MI65 (1042), and purple, e.g., MN58a (154). For complementation, see references 500 and 1041. Fine-structure mapping (500, 1042) needs reevaluation because of new information on the location of the arg-6 marker (797).	IR	B
su(met-7)	IR. Linked to al-2 (1%) (386). Selected as reversions of met-7 (4894) by Giles (386). All spontaneous reversions were at this locus. Suppresses met-7(4894) and met-2 (H98). Not tested for suppression of other alleles or loci. Suppressed strains attain wild-type growth on minimal medium after initial retardation, which is alleviated by methionine (386). This is apparently the suppressor used by Fischer (347) to show that the suppressor restores cystathionase I and II activities to 4894 and H98, respectively. Called S-1, FGSC 39.	IR	B