FGSC #6760

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Reporting Genes: al-1 (age-3 (=ylo-4)

Species: crassa

Allele: 32

Alternate Strain Number: 32

Mutagen: UV

Depositor: KDM

Linkage Group: IR

Mating Type: a

Species Number: 10

Genetic Background: SL2

Opposite Mating Type: 6759

ref1: Munkres & Furtek Mech. Age. Dev. 1984 25:63-77, https://doi.org/10.1016/0047-6374(84)90130-1

Deposit Sheet ↗

Genes

Locus	Cultural Requirements	Link Group	Type
ylo-4	A pigmenting al-1 allele, called age-3 as well as ylo-4.		B
age-3	IR. Right of age-1 and un-18. (705, K.D. Munkres, personal communication) Reduced conidial longevity. Differs from age-1 and age-2mutants in having yellow conidia and normal genesis of conidiophores (705).	IR	B
al-1	IR. Right of hom (<1%), arg-6 (<1 to 4%), T(T54M94), and al-2. Left of lys-3 (9%). (797, 808; D.D. Perkins, unpublished data). (482) Carotenoids abnormal. Strains carrying the various alleles differ widely in phenotype, ranging from white (e.g., 4637) and "aurescent" (pigment in peripheral conidia and conidiophores, 34508) to yellow mycelia and conidia (e.g., ALS4 and RES-25). See, for example, reference 1042. Strains carrying alleles ALS-14, RES-6, 34508, and RES-25 contain large amounts of phytoene (99 to 100% of the total neutral carotenoids), suggesting a lesion that affects phytoene dehydrogenase (398, 1039) (see Fig. 9). Strains carrying allele RWT-ylo accumulate zeta carotene and smaller amounts of neurosporene, suggesting a leaky block of the step between these intermediates (1071). It is not known whether phytoene dehydrogenase catalyzes the whole series of dehydrogenations or whether leakiness of this enzyme accounts for the different mutant phenotypes. For complementation tests, see references 500, 1039, and 1041. Fine-structure mapping (500, 1042). Translocation T(4637), inseparable from al-1, was the first albino mutation and one of the first chromosome rearrangements in Neurospora to be identified and studied (656). Allele 34508 called aur: aurescent.	IR	B