FGSC #6749

Reporting Genes: age-1.8

Species: crassa

Allele: 16

Alternate Strain Number: 16-2

Mutagen: S

Depositor: KDM

Linkage Group: IR

Mating Type: A

Species Number: 10

Genetic Background: SL2

ref1: Munkres & Furtek Mech. Age. Dev. 1984 25:63-77, https://doi.org/10.1016/0047-6374(84)90130-1

Genes

Locus	Cultural Requirements	Link Group	Type
age-1.8	IR. Symbol used for a series of many linked loci distal to nit-1, possibly redundant complexes. Individual loci symbolized as 1.3, 1.5, etc. Prototype age 1.5 is right of so(14%) and left of aro-8 (7.6%); age 1.3 maps at same site as so, q.v. (K.D. Munkres, personal communication). Reduced conidial longevity in the light. Not expressed in the dark, or in the light with vitamin E or reduced glutathione. Deficient in an isozyme of catalase, in mitochondrial superoxide dismutase, and in other enzymes involved in destroying free radicals and peroxides. Scored by plating efficiency after incubation of mature slant cultures at 30 C, 100% relative humidity, in continuous white fluorescent light, 24 J/square meter. Also scored by a defect in conidiophorogenesis on Vogel sorbose- sucrose plates. Initial mutants selected as spontaneous variants from f1 of Oak Ridge wild types; variants with increased conidial longevity can also be selected. High spontaneous mutation rate. Longer life span correlated with slower growth. (702, 704, 705, 708; K. D. Munkres, personal communication)	IR	B

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