FGSC #6441

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Reporting Genes: mus-29 trp-2

Species: crassa

Allele: FK119 41

Alternate Strain Number: M2407

Depositor: EK

Linkage Group: VIL R

Mating Type: a

Species Number: 10

Opposite Mating Type: 6440

Deposit Sheet ↗

Genes

Locus	Cultural Requirements	Link Group	Type
trp-2	VIR. Right of del (0 to 13%). Left of un-23 (5 to 27%), T(OY320), and ws-1 (38%) (818, 822, 1019, PB). Uses kynurenine, anthranilic acid, indole, or tryptophan (96). Kynurenine is utilized by conversion to anthranilate (447). Inferred to be the structural gene for the alpha subunit of the anthranilate synthetase complex (546). The gene product catalyzes anthranilate synthesis with ammonia but not with glutamine as the amino donor (29). Specifies anthranitate synthetase (glutamine linked) in collaboration with trp-1 in trifunctional trp-1+-trp-2+ enzyme aggregate (181, 259) (Fig. 11); see trp-1. Nonsense allele used to isolate supersuppressors (954) and to study enzyme complex restored by supersuppressors (183).	VIR	B
mus-29	VIL. Between chol-2 (14%) and lys-5 (15%). Moderately sensitive to MMS and histidine, low but consistant sensitivity to gamma rays and bleomycin, and not sensitive to UV or mitomycin C. Reduced conidial viability. Homozygous sterile. One mutant, FK119.	VIL	B