FGSC #6412

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Reporting Genes: pan-1;mus-11

Species: crassa

Allele: 5531;FK117

Alternate Strain Number: M2386

Depositor: EK

Linkage Group: IVR;VR

Mating Type: a

Species Number: 10

Opposite Mating Type: 6411

Deposit Sheet ↗

Genes

Locus	Cultural Requirements	Link Group	Type
mus-11	VR. Linked to pab-2 (539), near his-6 (E. Kafer, personal communication). Extremely sensitive to methyl methane sulfonate and histidine; also sensitive to X rays, nitrosoguanidine, and mitomycin C (< X rays). High spontaneous mutation. Little or no mutability by UV or X rays. Homozygous barren. Reduced conidial viability (537, 539). Not allelic with Mei-2 (939).	VR	B
pan-1	IVR. Between ad-6 (1 to 2%) and cot-1 (2 to 3%) (633, 692, PB). (482). cel, col-1, int, pho-3, and thi-5 all appear to be closely linked in this crowded region. Requires intact pantothenic acid for growth under standard conditions. Able to synthesize both precursors, beta-alanine and pantoyl lactone (1058). Ability to synthesize pantothenic acid from beta-alanine plus pantoyl lactone is demonstrable in vitro but not in vivo unless cultures are aerated (1111, 1113, 1114). Unlike pan-2, pan-1 has no effect on ascospore ripening in heterozygous crosses. Called group A. For alleles see reference 138.	IVR	B