FGSC #4197

Reporting Genes: uvs-4 leu-1

Species: crassa

Allele: ALS12 33757

Alternate Strain Number: M1389 a

Depositor: EK

Linkage Group: IIIR

Mating Type: a

Species Number: 10

ref1: Kafer 1982. Neurospora Newsl. 29:41-44, https://doi.org/10.4148/1941-4765.1645

Genes

Locus	Cultural Requirements	Link Group	Type
leu-1	IIIR. Between ad-4 (1 to 5%) and his-7 (8%) (219, 578, 815, 1052). (868)Requires leucine (867, 868). Lacks beta-isopropylmalate dehydrogenase (426) (Fig. 15). Accumulates alpha-isopropylmalate and beta-isopropylmalate (427). Synthesis of the enzyme also requires the function of regulatory gene leu-3+ and the presence of alpha-isopropylmalate, which acts as inducer (427). Resistant to aminotriazole (D. D. Perkins, unpublished data). Female sterile (O. M. Mylyk, personal communication). Used to study reversion and competition in heterokaryons (901).	IIIR	B
uvs-4	IIIR. Left of ad-4 (4%) (932). Sensitive to UV (273, 932, 933) and histidine (932). Moderately sensitive to methyl methane sulfonate (537). Insensitive or only slightly sensitive to nitrosoguanidine (537, 933); no increased sensitivity to ionizing radiation (940) or mitomycin C (195, 537). Probably normal spontaneous mutation (275). Reduced UV-induced mutation (273). For mutation induction by other agents, see reference 940. Homozygous fertile; no effect on intragenic or intergenic recombination. Ascospore viability and early growth severely impaired in homozygous crosses (932). Recessive in heterokaryons (979).	IIIR	B

Neurospora Crassa Wikipedia