FGSC #3905

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Reporting Genes: mus-13 al-2;pan-1

Species: crassa

Allele: SC13 15300;5531

Alternate Strain Number: M13-11

Mutagen: NG

Depositor: NCM

Linkage Group: IR IR;IVR

Mating Type: a

Species Number: 10

Genetic Background: M

ref1: DeLange & Mishra Genetics 97:247-259 1981, https://doi.org/10.1093/genetics/97.2.247

ref2: DeLange and Mishra Mut. Res. 96:187 1982, https://doi.org/10.1016/0027-5107(82)90086-0

Deposit Sheet ↗

Genes

Locus	Cultural Requirements	Link Group	Type
mus-13	IR. Right of al-2 (18%). Growing mycleia are slightly sensitive when grown on MMS medium. Growth is poor on minimal medium. Conidia are not sensitive to MMS, radiation, or histidine. Fertility is normal. One mutant, SC28.	IR	B
pan-1	IVR. Between ad-6 (1 to 2%) and cot-1 (2 to 3%) (633, 692, PB). (482). cel, col-1, int, pho-3, and thi-5 all appear to be closely linked in this crowded region. Requires intact pantothenic acid for growth under standard conditions. Able to synthesize both precursors, beta-alanine and pantoyl lactone (1058). Ability to synthesize pantothenic acid from beta-alanine plus pantoyl lactone is demonstrable in vitro but not in vivo unless cultures are aerated (1111, 1113, 1114). Unlike pan-2, pan-1 has no effect on ascospore ripening in heterozygous crosses. Called group A. For alleles see reference 138.	IVR	B
al-2	IR. Right of os-5 (<1%) and T(STL76). Left of arg-6(1%) and al-1 (797, 802, 808, 816, 818). Included in duplications from Tp(T54M94), confirming location left of arg-6(808). (482) Carotenoids absent or abnormal, but steroids produced (398). Blocked in microsomal fraction and defective in phytoene synthetase (445), a particulate enzyme (445 and references cited therein) (Fig. 9). Tracer experiments indicate a lesion between prephytoene pyrophosphate and phytoene (572). Alleles include those resulting in white and pale rose-white, e.g., 15300 and Y254MI65 (1042), and purple, e.g., MN58a (154). For complementation, see references 500 and 1041. Fine-structure mapping (500, 1042) needs reevaluation because of new information on the location of the arg-6 marker (797).	IR	B