FGSC #3365

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Reporting Genes: pyr-2

Species: crassa

Allele: no#;no#;R59

Alternate Strain Number: R59,F84-1-107A

Mutagen: UV

Depositor: SRG

Linkage Group: --

Mating Type: A

Species Number: 10

Genetic Background: M

ref1: Reichembecher et al 1978 J Bact 133:802-810, https://doi.org/10.1128/jb.133.2.802-810.1978

ref2: https://doi.org/10.1128/jb.133.2.794-801.1978

Deposit Sheet ↗

Genes

Locus	Cultural Requirements	Link Group	Type
pyr-2	IVR. Right of nit-3 (2 to 9%). Left of mat (3%) and the T(NM152) right breakpoint (633, 812, 1000, PB). (482)Requires uracil or other pyrimidine. Lacks orotidine 5'-monophosphate pyrophosphorylase activity (133, 134) (Fig. 20). Needs medium containing >0.5 mg of uracil per ml for optimal growth. Allele 38502 is leaky. Pyrimidine biosynthetic pathway, showing sites of gene action (134, 456, 841, 1140). Carbamyl phosphate for arginine synthesis is made as a separate pool by a different enzyme system (see arg-2, arg-3, Fig. 10). Interchange between the two pools occurs only in certain mutant combinations. ATP, Adenosine 5'-monophosphate.	IVR	B