FGSC #3132

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Reporting Genes: T(VII->IV)T54M50,het-e nic-3

Species: crassa

Allele: T54M50 Y31881

Alternate Strain Number: 74-1083

Depositor: DDP

Linkage Group: VL;IVR;VL L

Mating Type: A

Species Number: 10

Opposite Mating Type: 3133

Deposit Sheet ↗

Genes

Locus	Cultural Requirements	Link Group	Type
nic-3	VIIL. Right of spco-4 (1%) and do (3%). Left of thi-3 (9 to 27%) and csp-2 (16 to 22%) (539, 812, 816, PB). (M.K. Allen, cited in references 718 and 789) Uses nicotinic acid, nicotinamide, 3-hydroxyanthranilic acid, 3-hydroxykynurenine, or high concentrations of quinolinic acid (96, 1168). Accumulates alpha-N-acetylkynurenine; blocked in conversion of kynurenine to 3-hydroxykynurenine (1168) (Fig. 18). Pyridine nucleotide levels (111). Pathway from tryptophan to nicotinic mononucleotide, showing sites of gene action (96, 100, 368, 1168). The enzymatic reactions between 3-hydroxyanthranilate and nicotinic mononucleotide have not been demonstrated directly in Neurospora.	VIIL	B
T(VII->IV)T54M50	Translocation		B
het-e	VIIL. Left of nic-3 (28%) (1144). Included in duplications from T(T54M501)(803).Killing reaction after fusion of het-E and het-e is more rapid and severe, and growth inhibition of strains carrying het-E/het-e duplications is more severe than for strains carrying incompatible combinations of het-c or of mating type alleles (803, 1144). Photograph of heterozygous duplication colony (729).	VIIL	B