FGSC #2514

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Reporting Genes: csp-1;nic-3

Species: crassa

Allele: UCLA37;Y31881

Depositor: CPS

Linkage Group: IL;VIIL

Mating Type: A

Species Number: 10

ref1: https://doi.org/10.1093/genetics/78.2.679

Deposit Sheet ↗

Genes

Locus	Cultural Requirements	Link Group	Type
csp-1	IL. Between arg-3 (1%) and the T(39311) right breakpoint (972, PB). Conidia fail to separate and become airborne. Photograph (972). Recessive. Cultures on agar readily scored by the "tap test." In water, conidia are freed at 1/10 the wild-type concentration (972). Used in connection with bd for study of circadian rhythms (e.g., reference 114). Useful in student laboratories to avoid contamination (966). Carotenoids tend to be yellowish in young cultures (PB).	IL	B
nic-3	VIIL. Right of spco-4 (1%) and do (3%). Left of thi-3 (9 to 27%) and csp-2 (16 to 22%) (539, 812, 816, PB). (M.K. Allen, cited in references 718 and 789) Uses nicotinic acid, nicotinamide, 3-hydroxyanthranilic acid, 3-hydroxykynurenine, or high concentrations of quinolinic acid (96, 1168). Accumulates alpha-N-acetylkynurenine; blocked in conversion of kynurenine to 3-hydroxykynurenine (1168) (Fig. 18). Pyridine nucleotide levels (111). Pathway from tryptophan to nicotinic mononucleotide, showing sites of gene action (96, 100, 368, 1168). The enzymatic reactions between 3-hydroxyanthranilate and nicotinic mononucleotide have not been demonstrated directly in Neurospora.	VIIL	B