FGSC #1573

Reporting Genes: [stp];al-2;ad-4(F4)

Species: crassa

Allele: 15300;F4

Alternate Strain Number: 30a-1

Depositor: HB

Mating Type: A

Species Number: 10

Genetic Background: M

ref1: McDougall and Pitenger 1966. Genetics 54:551-565, https://www.genetics.org/content/genetics/54/2/551.full.pdf

ref2: Griffiths et al. 1968. Neurospora Newsl. 13:16-17, https://doi.org/10.4148/1941-4765.1935

Genes

Locus	Cultural Requirements	Link Group	Type
{stp}			B
al-2	IR. Right of os-5 (<1%) and T(STL76). Left of arg-6(1%) and al-1 (797, 802, 808, 816, 818). Included in duplications from Tp(T54M94), confirming location left of arg-6(808). (482) Carotenoids absent or abnormal, but steroids produced (398). Blocked in microsomal fraction and defective in phytoene synthetase (445), a particulate enzyme (445 and references cited therein) (Fig. 9). Tracer experiments indicate a lesion between prephytoene pyrophosphate and phytoene (572). Alleles include those resulting in white and pale rose-white, e.g., 15300 and Y254MI65 (1042), and purple, e.g., MN58a (154). For complementation, see references 500 and 1041. Fine-structure mapping (500, 1042) needs reevaluation because of new information on the location of the arg-6 marker (797).	IR	B
ad-4(F4)	Requires adenine. Cannot use hypoxanthine or inosine.	IIIR	B

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