FGSC #210

Reporting Genes: asco trp-2

Species: crassa

Allele: 37402 75001

Alternate Strain Number: 6008

Depositor: DDP

Linkage Group: VIL VIR

Mating Type: A

Species Number: 10

ref1: Stadler 1956 Genetics 41:528-543, https://www.genetics.org/content/41/4/528.long

Genes

Locus	Cultural Requirements	Link Group	Type
asco	an allele of lys-5. Requires lysine. ascospores fail to darken.	VIL	B
trp-2	VIR. Right of del (0 to 13%). Left of un-23 (5 to 27%), T(OY320), and ws-1 (38%) (818, 822, 1019, PB). Uses kynurenine, anthranilic acid, indole, or tryptophan (96). Kynurenine is utilized by conversion to anthranilate (447). Inferred to be the structural gene for the alpha subunit of the anthranilate synthetase complex (546). The gene product catalyzes anthranilate synthesis with ammonia but not with glutamine as the amino donor (29). Specifies anthranitate synthetase (glutamine linked) in collaboration with trp-1 in trifunctional trp-1+-trp-2+ enzyme aggregate (181, 259) (Fig. 11); see trp-1. Nonsense allele used to isolate supersuppressors (954) and to study enzyme complex restored by supersuppressors (183).	VIR	B

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