Gene: methionine-1 IVR
methionine-1
locus: met-1
locus_name: methionine-1
organism_type: B
chromosome_number: IV
chromosome_side: R
link_group: IVR
cultural_requirements: IVR. Right of oxD (3%) and the T(S1229) left breakpoint. Left of col-4 (4%) (55, 158, 718, 768, 808). Uses methionine but not homocysteine (469) (Fig. 17). Lacks methylene tetrahydrofolate reductase and, thus, lacks the coenzyme needed for transmethylating homocysteine (124, 963, 964). A report that the mutant met-1 also lacks cystathionine-gamma-synthase (547) proved incorrect; the error resulted because methyl tetrahydrofolate is an essential activator of cystathionine-gamma-synthase (965). Methylene tetrahydrofolate reductase is feedback-inhibited by S-adenosylmethionine (124). Used in heteroallelic duplications from T(S1229) to assay mitotic recombination (56).
enzyme_id: 135
Enzyme: methylene tetrahydrofolate reductase
anid_name:
near_l: oxD (3%) and T(S1229) left breakpoint
near_r: col-4 (4%)
neu_name:
supplement: methionine
image_url:
Strains
| FGSC # | Reporting Genes | Species |
|---|---|---|
| FGSC #317 | met-1 | crassa |
| FGSC #408 | Has been replaced by strain number: 559 | crassa |
| FGSC #559 | met-1 | crassa |
| FGSC #560 | Has been replaced by strain number: 3049 | crassa |
| FGSC #1277 | met-1 | crassa |
| FGSC #1278 | met-1 | crassa |
| FGSC #1325 | oxD met-1;inl | crassa |
| FGSC #3049 | met-1 | crassa |
| FGSC #3050 | met-1 | crassa |
| FGSC #3274 | met-1 | crassa |
| FGSC #3276 | met-1 | crassa |
| FGSC #3281 | met-1 | crassa |
| FGSC #6469 | mus(FK133);met-1 | crassa |
| FGSC #6470 | mus(FK133);met-1 | crassa |
| FGSC A1090 | met,bi, green, fluG701 suppressor? | nidulans |
References
