Genes beginning with "x"

xdh-1 : xanthine dehydrogenase-1

II. Linked to pe (14%), alc-1 (24%) (1712).

Lacks xanthine dehydrogenase (EC (XDH; xanthine oxidase). Defective in purine catabolism, of which XDH catalyzes the first step (Fig. 8). Unable to use hypoxanthine as the sole nitrogen source. Mutants nit-1, -7, -8, and -9 are deficient in XDH activity because of a defect in the molybdenum-containing cofactor that is common to XDH and nitrate reductase (1441, 2101, 2102).

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