Announcements from the FGSC

 

The FGSC is located in the
Department of Plant Pathology,
Kansas State University


Announcements

Save the Dates!

The Neurospora 2018 Conference at Asilomar will be held October 18- 21, 2018.


The FGSC moved from Kansas City to Manhattan Kansas (about 200 Km) in November 2014. This is the 4th time the FGSC has relocated since it was founded in 1960



Jobs

Post-doctoral fellowships in Molecular Mycology / Cell Biology / Genomics
Field of knowledge: Microbiology - FAPESP process: 2016/07870-9
Project title: The influence of Mitogen Activated Protein kinases (MAPK) on the expression of genetic determinants important for Aspergillus fumigatus virulence Working area: Molecular Microbiology / Cell Biology / Genomics
Principal investigator: Gustavo H. Goldman / Iran Malavazi
Units/Institutions: Faculdade de Ciencias Farmaceuticas de Ribeirao Preto, Universidade de Sao Paulo and Departamento de Genética e Evolucao, Centro de Ciencias Biologicas e da Saude, Universidade Federal de Sao Carlos, Sao Carlos, Sao Paulo, Brazil
Deadline for submissions: November 30, 2017
Locals: Faculdade de Ciencias Farmaceuticas de Ribeirao Preto, Universidade de Sao Paulo and Departamento de Genetica e Evolucao, Centro de Ciencias Biologicas e da Saude, Universidade Federal de São Carlos, Sao Carlos, Sao Paulo, Brazil
Summary The project " The influence of Mitogen Activated Protein kinases (MAPK) on the expression of genetic determinants important for Aspergillus fumigatus virulence ", funded by FAPESP (2016/07870-9) and coordinated by Prof. Dr. Gustavo H. Goldman, offers vacancies for postdoctoral fellows willing to collaborate in its development. The group's main research interests include understanding the influence of Mitogen Activated Protein kinases (MAPK) on the A. fumigatus virulence.
The grants will be financed by FAPESP, for a minimum period of 2 years. The value of the scholarship will be in accordance with FAPESP standards for post-doctorates (www.fapesp.br/3162). Installation assistance is available and subject to eligibility.
Vacancy 1: A Post-Doctoral scholarship is available to work in the Laboratory of Molecular Biology – FCFRP (USP), Ribeirao Preto – Sao Paulo state, under the supervision of Dr. ustavo H. Goldman. The selected candidate will carry out research to evaluate the influence of HOG1 MAPK (SakA and MpkC) on the A. fumigatus virulence.
Applicant requirements
Required:
Ph.D. (completed in the last 5 years) in Molecular Microbiology, Molecular Biology, Biochemistry, Cell Biology, or similar area;
Fluency in English;
Knowledge of microbiology.
Desirable:
Genomics, and basic knowledge in bioinformatics;
Experience in microscopy, cell biology;
Experience in molecular biology techniques: gene expression and protein evaluation;
RNA extraction, library preparation, RNAseq, qPCR, sequencing.
Experience in candidate gene validation techniques by molecular biology: DNA / RNA extraction; qPCR; Western blot and other methods for evaluating proteinsand protein interaction.
Vacancy 2: The Post-Doctoral scholarship is available to work at Departamento de Genetica e Evolucao, Centro de Ciências Biológicas e da Saude, Universidade Federal de Sao Carlos, Sao Carlos, Sao Paulo state, under the supervision of Prof. Dr. Iran Malavazi. The selected candidate will carry out research to evaluate the influence of MpkA MAPK on the A. fumigatus virulence. Required: Ph.D. (completed in the last 5 years) in Molecular Microbiology, Molecular Biology, Biochemistry, Cell Biology, or similar area; Fluency in English; Knowledge of microbiology. Desirable:
Genomics, and basic knowledge in bioinformatics;
Experience in microscopy, cell biology;
Experience in molecular biology techniques: gene expression and protein evaluation;
RNA extraction, library preparation, RNAseq, qPCR, sequencing.
Experience in candidate gene validation techniques by molecular biology: DNA / RNA extraction; qPCR; Western blot and other methods for evaluating proteins and protein interaction.


For proposal submission and to apply, Interested candidates should contact Nicola Conran / Prof. Fernando F. Costa by e-mail via the "Apply for this job" button, specifying in the e-mail title the scholarship to which they are applying (Vacancy 1 or Vacancy 2). Attaching:
a) A cover letter describing your interest in the vacancy (Vacancy 1 or 2)
b) Curriculum vitae in pdf, including a list of publications and experiences;
c) Contact information (e-mail, telephone) of two professionals who can provide letters of recommendation.
This opportunity is open to candidates of any nationalities. The selected candidate will receive a FAPESP's Post-Doctoral fellowship in the amount of R$ 6.819,30 monthly and a research contingency fund, equivalent to 15% of the annual value of the fellowship which should be spent in items directly related to the research activity. More information about the fellowship is at: site da FAPESP
Para a FAPESP:
Field of knowledge: Microbiology
FAPESP process: 2016/07870-9
Project title: The influence of Mitogen Activated Protein kinases (MAPK) on the expression of genetic determinants important for Aspergillus fumigatus virulence Working area: Molecular Microbiology/Molecular Biology/Cell Biology
Start: 05/01/2018
Principal investigator: Gustavo H. Goldman
Unit/Instituition: Faculdade de Ciencias Farmaceuticas de Ribeirao Preto, Universidade de Sao Paulo
Deadline for submissions: November 30, 2017
Publishing date: Locale: Faculdade de Ciências Farmacêuticas de Ribeirao Preto, Universidade de Sao Paulo and Departamento de Gentica e Evolucao, Centro de Ciências Biologicas e da Saude, Universidade Federal de Sao Carlos, Sao Carlos, Sao Paulo, Brazil
E-mail for proposal submission: ggoldman@usp.br and imalavazi@ufscar.com
Summary
MAP kinases and phosphatases are the main signaling pathways of tolerance to different kinds of stresses in eukaryotes. The multifactorial nature of A. fumigatus virulence and pathogenicity program in the mammalian host places the response to different kinds of stresses as one of the most important responses in the process of establishment of this organism as a pathogen. These signaling pathways are important for the cell wall biosynthesis and remodeling, responses to oxidative stress and antifungal drugs, biofilm formation and adhesion, and possibly other essential features not yet investigated such as, blood dissemination from the pulmonary epithelium and strategies of immunological evasion. The understanding of the metabolic nets that are coordinated by MAP kinases will provide an opportunity for the construction of the signaling pathways that are important for stress tolerance and the establishment of the A. fumigatus virulence and pathogenicity program in mammals. Thus, the main objectives of this project are: (i) the identification of specific transcription factors that are activated by different kinds of stress and that are dependent on MAP kinases; (ii) the identification of proteins that interact physically with the MAP kinases when A. fumigatus is exposed to different kinds of stresses; (iii) the investigation of a possible "crosstalk" among the different A. fumigatus MAP kinases during different kinds of stresses; (iv) the molecular characterization of MpkB and the verification if this MAP kina
se is important for A. fumigatus virulence, and (v) the characterization of the interaction between the A. fumigatus mutants generated in this study and the immunosupressed and imunocompetent murine hosts. The selected candidate will receive a FAPESP Post-Doctoral fellowship in the amount of R$ 6.819,30 monthly and a research contingency fund, equivalent to 15% of the annual value of the fellowship which should be spent on items directly related to the research activity, as well as displacement funding, if necessary and applicable. More information about the fellowship is at: fapesp.br/en/postdoc.
Further information and application: ggoldman@usp.br and imalavazi@ufscar.com

Post-Doctoral position at the Institute of Chemistry, UNESP, Araraquara, São Paulo State, Brazil

The project "Neurospora crassa filamentous fungus as a model organism for the identification and characterization of new proteins/transcription factors regulating the carbohydrate metabolism", funded by FAPESP (São Paulo State Research Foundation) has one Post-Doctoral position for application. The selected candidate will be working with Prof. Dr. Maria Célia Bertolini at the Institute of Chemistry, UNESP, Araraquara, São Paulo State, Brazil. The candidates should demonstrate previous experience in Biochemistry and in basic and advanced Molecular Biology. Candidates should send (up to September 10, 2017) the following documents to Prof. Maria Célia Bertolini (mcbertol@iq.unesp.br): a letter including the scientific experience, a short CV, and names and addresses of two researchers as references. The value of the FAPESP Postdoctoral scholarship is R$ 6.819,30 monthly (about U$ 2,000.00, free of taxes).




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